Comparison of different TIRM schemes based on the DSM
N. Grishina*,1, E. Eremina2, Y. Eremin1 and T. Wriedt3
- 1 Moscow Lomonosov State University, Vorobyov's Hills, 119991 Moscow, Russia.
- 2 University of Bremen, Badgasteiner str.3, 28359 Bremen, Germany.
- 3 Institute of Materials' science, Badgasteiner str.3, 28359 Bremen, Germany.
Total Internal Reflection Microscopy (TIRM) is an effective technique to measure weak interactions between colloidal particles in solution and a flat surface. In this paper, the Discrete Sources Method (DSM) has been applied to model different TIRM measuring schemes to find the most appropriate one for the determination of the distance between the particle and flat surface. It has been found that placing the collector beneath the prism gives a considerable advantage as compared to the conventional TIRM design.
- * Corresponding author